The subject of the study is the state of tax control as a significant institution of the Plant Cages tax system in Russia.An analysis of changes in legislation on taxes and fees, literature and taxation practices has pointed to the urgency of the problem of incomplete taxation by tax authorities during tax control.The purpose of the article is to s
Summary: In direct lineage conversion, transcription factor (TF) overexpression reconfigures gene regulatory networks (GRNs) to reprogram cell identity.We previously developed CellOracle, a computational method to infer GRNs from single-cell transcriptome and epigenome data.Using inferred GRNs, CellOracle simulates gene expression changes in respon
Abstract Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation, and it has been studied extensively since its discovery in 2012.Induced by iron overload and ROS accumulation, ferroptosis is modulated by various cellular metabolic and signaling pathways.The GSH-GPX4 pathway, the FSP1-CoQ10 pathway, the GCH1-BH4 p
Abstract Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many Wooden Ornament Display Stand tropical and sub-tropical countries where the transmission vectors Aedes spp.mosquitoes resides.There are four serotypes of the virus.Each serotype is antigenically different, meaning they elicit heterologous antibodies.Infection with o
Abstract In recent decades, a new method of cellular immunotherapy was introduced based on engineering and empowering the immune effector cells.In this type of immunotherapy, the Wooden Ornament Display Stand immune effector cells are equipped with chimeric antigen receptor (CAR) to specifically target cancer cells.In much of the trials and experim